Status:
UNKNOWN
Neurosteroids and Acute Alcohol Intoxication in Humans
Lead Sponsor:
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Conditions:
Alcohol Intoxication
Eligibility:
All Genders
21-45 years
Phase:
PHASE1
Brief Summary
1\. The major aims are to assess: (1) the relationship of basal and alcohol-induced neurosteroid and GABA levels to the degree of acute alcohol intoxication in healthy male and female volunteers; and ...
Detailed Description
2\. BACKGROUND Neurosteroid Responses to Alcohol Administration: Alcohol likely interacts with the brain GABA-A receptor complex via two distinct manners: a direct effect (Grobin et al 1998), and an i...
Eligibility Criteria
Inclusion
- drinks alcohol more than 6 times a year.
- can understand english well enough to perform the required tasks.
- is in general good health.
Exclusion
- having a member of immediate family who is alcoholic.
- using drugs that would interfere with study.
- not able to tolerate 3 alcoholic drinks within 30 minutes.
Key Trial Info
Start Date :
May 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2009
Estimated Enrollment :
92 Patients enrolled
Trial Details
Trial ID
NCT00608686
Start Date
May 1 2004
End Date
March 1 2009
Last Update
December 19 2008
Active Locations (1)
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1
University of California, San Francisco
San Francisco, California, United States, 94143