Status:

TERMINATED

A Feasibility Study of Adaptive Intensity-Modulated Radiation Therapy

Lead Sponsor:

Washington University School of Medicine

Conditions:

Head and Neck Cancer

Eligibility:

All Genders

18+ years

Phase:

EARLY_PHASE1

Brief Summary

Patients with head and neck cancer and are schedule to receive standard radiation therapy known as IMRT to treat cancer

Detailed Description

In this study, we will plan additional measurements of the position of the patient's organs weekly during radiation treatment. We will analyze these measurements in order to evaluate whether we need t...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Age \>= 18
  • Karnofsky Performance Status of \>= 60
  • New diagnosis of head-and-neck cancer, all subsites included (i.e. nasopharynx, oropharynx, oral cavity, hypopharynx, larynx.)
  • All stages with measurable gross disease (\>= 1.0 cm) by CT imaging
  • Pathologic confirmation of squamous cell carcinoma by biopsy or cytology
  • Signed study-specific consent form
  • Sequential or concurrent chemotherapy is allowed but not mandated. (no chemotherapy is allowed if patient is judged not to be a candidate for chemotherapy by the medical oncologist)
  • Exclusion Criteria
  • Age \< 18
  • Karnofsky Performance Status \< 60
  • Radiographic or pathologic evidence of distant metastatic disease (i.e. other than cervical lymph nodes)
  • Prior radiation therapy to the head-and-neck region

Exclusion

    Key Trial Info

    Start Date :

    January 1 2007

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    January 1 2008

    Estimated Enrollment :

    5 Patients enrolled

    Trial Details

    Trial ID

    NCT00608751

    Start Date

    January 1 2007

    End Date

    January 1 2008

    Last Update

    May 24 2013

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Washington University School of Medicine

    St Louis, Missouri, United States, 63110