Status:
UNKNOWN
Rapid Diagnosis of Pulmonary Tuberculosis
Lead Sponsor:
University of Cape Town
Collaborating Sponsors:
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions:
Tuberculosis
Eligibility:
All Genders
12+ years
Phase:
NA
Brief Summary
The purpose of this study is to test whether a saline nebulization (breathing in a mist of moist air through a mask) will help an individual cough up a better sputum sample to test for tuberculosis (T...
Detailed Description
Early case detection, treatment, and prompt household contact investigation, depend on rapid microbiological confirmation, by direct smear microscopy of acid-fast bacilli, in patients with suspected p...
Eligibility Criteria
Inclusion
- Adolescents and adults with suspected pulmonary tuberculosis who are referred, or self-refer, to health services clinics for investigation for tuberculosis, will be eligible to participate.
Exclusion
- Failure to obtain informed consent (including failure to consent for either sputum collection procedures or failure to consent for HIV testing);
- Age less than 12 years;
- A history of asthma;
- A history of heart disease;
- A history of cardiac arrhythmia;
- Inability to tolerate sputum induction procedures;
- Inability to return for study follow-up visit;
- Need for hospital-based in-patient treatment or supplemental oxygen therapy;
- Other acute or chronic lung disease that may compromise lung function;
- Current anti-tuberculous therapy.
Key Trial Info
Start Date :
February 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2013
Estimated Enrollment :
600 Patients enrolled
Trial Details
Trial ID
NCT00608790
Start Date
February 1 2008
End Date
April 1 2013
Last Update
July 24 2012
Active Locations (1)
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1
University of Cape Town
Cape Town, South Africa