Status:

COMPLETED

Almorexant (ACT 078573) in Adult Subjects With Chronic Primary Insomnia

Lead Sponsor:

Midnight Pharma, LLC

Conditions:

Primary Insomnia

Eligibility:

All Genders

18-64 years

Phase:

PHASE3

Brief Summary

A polysomnography study to evaluate the effect, safety and tolerability of oral administration of almorexant (ACT 078573) in adult subjects with primary insomnia.

Eligibility Criteria

Inclusion

  • Adult subjects (18-64 years) with a diagnosis of primary insomnia.

Exclusion

  • History of any sleep disorder, or any Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) axis I disorder other than primary insomnia.
  • Sleep apnea, or restless legs syndrome.
  • Daytime napping of more than 1 hour per day.
  • Important caffeine consumption, heavy tobacco use, alcohol or drug abuse within 2 years prior to the screening visit.
  • Unwillingness to refrain from drugs, over-the-counter or herbal medication having an effect on sleep or behavior.

Key Trial Info

Start Date :

March 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2009

Estimated Enrollment :

709 Patients enrolled

Trial Details

Trial ID

NCT00608985

Start Date

March 1 2008

End Date

November 1 2009

Last Update

March 14 2016

Active Locations (91)

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Page 1 of 23 (91 locations)

1

Sleep Disorders Laboratory, Royal Adelaide Hospital

Adelaide, South Australia, Australia, 5000

2

Monash Adult Sleep Center, Monash Medical Centre

Clayton, Victoria, Australia, 3168

3

Western Hospitpal, Private Bag

Footscray, Victoria, Australia, 3011

4

Institute for Breathing and Sleep (IBAS)

Heidelburg, Victoria, Australia, 3084