Status:
UNKNOWN
Adverse Effects of Glucocorticoid Therapy on Bone in Childhood Crohn's Disease
Lead Sponsor:
University Hospital Birmingham
Collaborating Sponsors:
SHS International
Children's Memorial Research Foundation
Conditions:
Crohn Disease
Eligibility:
All Genders
7-17 years
Phase:
PHASE4
Brief Summary
This study will compare two current first-line treatments for childhood Crohn's Disease, steroids versus a liquid diet, and determine the effects of these treatments on bone health, quality of life an...
Detailed Description
Crohn's Disease is a very serious inflammatory gut disorder that often first presents in childhood. Once present, the underlying condition remains for life. It usually responds well to medical treatme...
Eligibility Criteria
Inclusion
- Active Crohn's Disease with PCDAI \> 20
- Aged 7 - 17 with possibility of 1 year follow-up
Exclusion
- Previous treatment for Crohn's Disease with liquid diet or glucocorticoid therapy
- Isolated orofacial granulomatosis
- Intravenous glucocorticoid therapy immediately indicated
- Planned surgical intervention for CD
Key Trial Info
Start Date :
February 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2010
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT00609752
Start Date
February 1 2008
End Date
January 1 2010
Last Update
December 30 2008
Active Locations (6)
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1
Bristol Royal Hospital for Sick Children
Bristol, Bristol, United Kingdom, BS2 8BJ
2
St George's University Hospital
London, London, United Kingdom, SW17 0QT
3
Royal Liverpool Children's Hospital
Liverpool, Merseyside, United Kingdom, L12 2AP
4
Oxford Children's Hospital
Oxford, Oxfordshire, United Kingdom, OX3 9DZ