Status:

COMPLETED

A Methodology Study Of Brain Imaging Of Pain-Killers In Post-Traumatic Neuropathic Pain Patients

Lead Sponsor:

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

Collaborating Sponsors:

University of Oxford

Conditions:

Pain

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

This study is a methodology study designed to discover whether a brain imaging technology is a better way of compare the relative sensitivities of fMRI and subjective psychometric assessments of pain ...

Eligibility Criteria

Inclusion

  • Diagnosis of neuropathic pain associated with brush allodynia in specific dermatomes.
  • Brush allodynia score of ≥4 and calculated average pain score of ≥3 on an 11-point numerical rating scale by the completion of down-titration of existing medications.
  • Right-handed

Exclusion

  • Subjects with trigeminal neuralgia, central pain (due to cerebrovascular lesions, multiple sclerosis and/or traumatic spinal cord injuries including spinal surgery).
  • Phantom limb pain, painful diabetic neuropathy.
  • Subjects with any other co-existing pain which he/she or a qualified pain physician cannot differentiate from NeP of peripheral origin.
  • Subjects with diabetes mellitus and with an HbA1C value of \>10% upon measurement at screening.

Key Trial Info

Start Date :

September 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2010

Estimated Enrollment :

18 Patients enrolled

Trial Details

Trial ID

NCT00610155

Start Date

September 1 2008

End Date

July 1 2010

Last Update

January 22 2021

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Pfizer Investigational Site

Portsmouth, Hampshire, United Kingdom, PO3 6AD

2

Pfizer Investigational Site

Solihull, West Midlands, United Kingdom, B91 2JL