Status:
COMPLETED
Magnetic Resonance Imaging in Patients With Breast Cancer
Lead Sponsor:
M.D. Anderson Cancer Center
Conditions:
Breast Cancer
Eligibility:
All Genders
18+ years
Brief Summary
The goal of this clinical research study is to learn how often magnetic resonance imaging (MRI) of the breast locates additional areas of cancer in the breast of patients with lobular cancer as well a...
Detailed Description
At MD Anderson, patients with breast cancer routinely have mammograms and ultrasounds to measure the size and extent of cancer. MRI of the breast is a technology that is better than mammograms and ul...
Eligibility Criteria
Inclusion
- Patients with pure invasive lobular carcinoma or mixed invasive ductal-lobular carcinoma with the ductal component not greater that 25% OR patients under the age of 40 at diagnosis, irrespective of tumor histology
- For women with invasive lobular carcinoma, if the pathology report from the diagnostic biopsy states that they have "predominantly" lobular histology or lobular cancer with "focal" areas/nests of ductal carcinoma, these cases will automatically be assumed to have at least 75% lobular component.
- Women with multifocal or multicentric breast cancer are eligible if any one of the biopsy confirmed tumors meets the histologic designations outlined in Inclusion criteria #1 and #2 above.
- Must be able to complete the MR examination within 30 days of mammography and ultrasound of the breast.
- Age \>18 years
- Surgery planned at MDACC
- Eastern Cooperative Oncology Group (ECOG) status 0-2
- Creatinine and glomerular filtration rate measured or calculated within 2 weeks of MRI date
Exclusion
- Patients receiving neoadjuvant chemotherapy
- Patients with pacemakers
- Patients with severe claustrophobia
- Obese patients exceeding the equipment weight limits and/or the circumference of the MRI portal
- Interval between MRI and conventional locoregional staging studies (mammography/breast US) greater than 30 days.
- Known allergy to gadolinium
- Patients with clips/prostheses/implanted devices that are not MRI compatible
- Compromised renal function, with a measured or calculated glomerular filtration rate of less than 60 ml/min/1.73m\^2.
Key Trial Info
Start Date :
January 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
96 Patients enrolled
Trial Details
Trial ID
NCT00610181
Start Date
January 1 2008
Last Update
July 1 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Texas MD Anderson Cancer Center
Houston, Texas, United States, 77030