Status:

COMPLETED

Study of T Cell Phenotype Activation Pathway in Human Alcoholic Liver Disease

Lead Sponsor:

Erasme University Hospital

Conditions:

Alcoholic Liver Disease

Chronic Hepatitis C Virus

Eligibility:

All Genders

18+ years

Brief Summary

Alcoholic liver disease is characterized by circulating T cell activation and liver T cell infiltration but their phenotype is poorly studied. The aim of the study is to test the hypothesis that the (...

Detailed Description

Consecutive patients undergoing transjugular liver biopsies for alcoholic liver disease or hepatitis C virus infection will be included in the study to measure plasma cytokines levels, peripheral bloo...

Eligibility Criteria

Inclusion

  • Alcohol excess intake and suspected liver disease
  • Alcohol excess intake and clinical liver cirrhosis
  • chronic hepatitis C virus infection and suspected liver disease
  • chronic hepatitis C virus infection and clinical liver cirrhosis

Exclusion

  • bacterial or fungal infection
  • immunosuppressive treatment
  • other causes of liver disease

Key Trial Info

Start Date :

January 1 2005

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 1 2008

Estimated Enrollment :

49 Patients enrolled

Trial Details

Trial ID

NCT00610597

Start Date

January 1 2005

End Date

January 1 2008

Last Update

February 8 2008

Active Locations (1)

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1

Hopital Erasme - Dpt of Gastroenterology

Brussels, Belgium