Status:
COMPLETED
The Effects of a Prostaglandin Inhibitor on Ovulation and the Menstrual Cycle
Lead Sponsor:
Oregon Health and Science University
Collaborating Sponsors:
Society of Family Planning
Conditions:
Ovulation (Follicular Rupture Yes/no)
Menstrual Cycles (Total Length, Bleeding Days)
Eligibility:
FEMALE
18-35 years
Phase:
NA
Brief Summary
The investigators propose to test the hypothesis that the use of a prostaglandin inhibitor will result in premature luteolysis (ovulation failure) in women.
Detailed Description
Currently available methods of emergency contraception (EC) only work during a very narrow time period prior to the hormonal trigger for ovulation or the release of an egg. Women having unprotected se...
Eligibility Criteria
Inclusion
- Age 18-35
- Normal menstrual periods (24-35 days)
- Good general health
- Willing to use a non-hormonal form of contraception for the entire study (Acceptable forms of contraception include condoms, spermicide, sexual contact with a sterilized partner, subject is surgically sterile, same-sex partner, Copper IUD and abstinence)
- Willing and able to return to clinic for bi-weekly blood tests
Exclusion
- Pregnant or breast feeding
- Polycystic ovarian disease
- Gastrointestinal conditions (i.e.gastric ulcer)
- Currently using birth control
- Known allergy to aspirin, non-steroidal anti-inflammatory drugs (NSAIDS) or Sulfa-drugs
- Diabetes
- Cardiac disease or hypertension
- Moderate to severe heartburn (GERD)
- Obesity (BMI greater than 30)
Key Trial Info
Start Date :
January 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2008
Estimated Enrollment :
11 Patients enrolled
Trial Details
Trial ID
NCT00614406
Start Date
January 1 2008
End Date
August 1 2008
Last Update
December 13 2012
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Oregon Health & Science University
Portland, Oregon, United States, 97239