Status:
TERMINATED
The Effects of Dexamethasone on the Duration of Sciatic Nerve Blocks
Lead Sponsor:
Loma Linda University
Conditions:
Total Knee Arthroplasty
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Dexamethasone is a commonly used steroid. This medication has been used for many years by physicians for many different indications. Recent articles, multiple case reports, and experience at this inst...
Eligibility Criteria
Inclusion
- Age 18-80 yrs, male or female subjects.
- Subjects must be scheduled to undergo total knee arthroplasty under general anesthesia with consent for a femoral and sciatic nerve block post operatively for pain control.
- American Society of Anesthesiology Class 1,2,3,or 4.
- Capable of speaking and understanding English sufficiently to provide written informed consent and able to respond when asked.
- Weight \> or equal to 60kg.
Exclusion
- Any allergies or hypersensitivity to ropivacaine or dexamethasone.
- Subject is on chronic steroids preoperatively for any reason.
- History of chronic pain syndrome (i.e. CPRS, Lumbar radiculopathy).
- History of documented or stated nerve damage or neuropathy to the surgical lower extremity.
- Contraindication to placement of sciatic nerve block.
- Sciatic block placement failure.
- Subject mistakenly receives steroids intraoperatively.
Key Trial Info
Start Date :
August 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2011
Estimated Enrollment :
43 Patients enrolled
Trial Details
Trial ID
NCT00616603
Start Date
August 1 2007
End Date
May 1 2011
Last Update
June 11 2014
Active Locations (1)
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1
Loma Linda University Medical Center
Loma Linda, California, United States, 92354