Status:
COMPLETED
Acute Effect of Fructose on Lipid Metabolism and Gender Differences
Lead Sponsor:
University of Lausanne
Conditions:
Lipid Metabolism
Eligibility:
All Genders
18-35 years
Phase:
NA
Brief Summary
It has been widely documented that fructose overfeeding increases plasma triglycerides and hepatic de novo lipogenesis, and impairs insulin sensitivity in healthy male volunteers. The effect of gender...
Detailed Description
The study is aimed at comparing the effects of oral fructose on several specific metabolic pathways in males and females.Participants will receive an isoenergetic diet containing 55% carbohydrate, 15%...
Eligibility Criteria
Inclusion
- Males and females
- Age 18-35
- Healthy
- Body mass indexes (BMI) between 19 and 25 kg/m2
- Informed consent obtained
Exclusion
- Smokers
- Alcohol intake \> 30g/day
- Drug abuse
- Diabetes mellitus
Key Trial Info
Start Date :
January 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2008
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT00620360
Start Date
January 1 2008
End Date
December 1 2008
Last Update
February 24 2012
Active Locations (1)
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1
Centre Hospitalier Universitaire Vaudois
Lausanne, Canton of Vaud, Switzerland, 1005