Status:
COMPLETED
T-Wave Alternans in Dialysis Patients
Lead Sponsor:
Northwestern University
Collaborating Sponsors:
General Electric
Conditions:
Sudden Cardiac Death
End Stage Renal Disease
Eligibility:
All Genders
18-90 years
Brief Summary
Sudden cardiac death due to arrhythmia is the leading cause of death in end-stage renal disease (ESRD) patients treated with hemodialysis (HD). As it is anticipated that the number of individuals with...
Detailed Description
The purpose of this study is to assess the degree of cardiac electrical instability at various times in the dialysis cycle. The hypothesis is that longer time intervals between hemodialysis results in...
Eligibility Criteria
Inclusion
- Patients with chronic ESRD who have been on HD for at least 3 months
- Subjects 18 to 90 years of age with one or more risk factors for coronary artery disease or sudden cardiac death, including diabetes, peripheral vascular disease, known coronary artery disease, or ejection fraction \< 40% by any imaging modality.
Exclusion
- Subjects unwilling or unable to give written informed consent.
- Patients unable to return for regularly scheduled dialysis treatments
- Atrial fibrillation or flutter at screening
- Major surgical procedure two months prior to enrollment
- High grade heart block or a permanent pacemaker in situ
- Patients with known allergies to adhesive tape
Key Trial Info
Start Date :
April 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2008
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00621426
Start Date
April 1 2007
End Date
May 1 2008
Last Update
March 12 2015
Active Locations (1)
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1
Northwestern University
Chicago, Illinois, United States, 60611