Status:
COMPLETED
The Role of COX-2 Inhibition in Salt Sensitivity of Blood Pressure
Lead Sponsor:
University of Delaware
Collaborating Sponsors:
Christiana Care Health Services
Conditions:
Hypertension
Eligibility:
All Genders
22-50 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine if the drug Celebrex changes the way the kidney gets rid of salt and maintains blood pressure.
Detailed Description
There have been many studies done with analgesics such as acetaminophen and non-steroidal anti-inflammatory drugs; however it is not understood how blood pressure changes while using Celebrex. The stu...
Eligibility Criteria
Inclusion
- healthy men and women
Exclusion
- history of heart disease
- have had heart surgery
- high blood pressure
- diabetes
- cancer
- any other disease such as kidney or neurological diseases
- taking medications such as aspirin or medicines for your heart or blood pressure
- have asthma or are allergic to sulfa drugs
- body mass index greater than 30
- use tobacco
- pregnant
- women using oral contraceptives or hormone replacement therapy
Key Trial Info
Start Date :
February 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2009
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT00624559
Start Date
February 1 2008
End Date
January 1 2009
Last Update
January 6 2012
Active Locations (1)
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1
University of Delaware
Newark, Delaware, United States, 19716