Status:
COMPLETED
The Effect of Allergen Inhalation on Sputum Myeloid and Plasmacytoid Dendritic Cells in Mild Atopic Asthmatics
Lead Sponsor:
Hamilton Health Sciences Corporation
Conditions:
Asthma
Eligibility:
All Genders
18-65 years
Phase:
EARLY_PHASE1
Brief Summary
Summary: A picture is emerging of dendritic cells migrating through the blood to the airways following allergen inhalation in atopic asthmatics. Although the Koh and McCarthy articles present novel f...
Detailed Description
Subjects will be put through two study periods. Each study period will consist of four visits and will be separated by 2-4 weeks. On the first visit, subjects will undergo screening procedures, includ...
Eligibility Criteria
Inclusion
- Mild atopic asthmatics, presently well controlled on ß2-agonists.
- Non-smokers.
- Baseline FEV1 more than 70% of predicted normal.
Exclusion
- Airway infection during the last 4 weeks.
- Exacerbation during the last 4 weeks.
- Inhaled or oral steroids during the last 4 weeks.
- Antihistamines during the last 48 hours.
- Asthma medication other than inhaled and/or oral ß2-agonists during the last 4 weeks.
- Pregnant women.
Key Trial Info
Start Date :
February 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2008
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT00625989
Start Date
February 1 2008
End Date
December 1 2008
Last Update
May 21 2018
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
McMaster University
Hamilton, Ontario, Canada, L8N 3Z5