Status:
TERMINATED
Pilot Trial of Intravenous Vitamin C in Refractory Non-Hodgkin Lymphoma (NHL)
Lead Sponsor:
Sidney Kimmel Cancer Center at Thomas Jefferson University
Conditions:
Non-Hodgkin Lymphoma
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
Eligible candidates will be adults with aggressive or very aggressive NHL (WHO classification diagnosis confirmed by histological tumor examination). Patients must have failed one or more prior NHL ch...
Eligibility Criteria
Inclusion
- Age greater than 18 years old
- Aggressive or very aggressive NHL
- Failed one or more therapies
- Patients must not have progressed within 60 days of last therapy
- Not received allogeneic stem cell transplant
- No reasonable standard therapeutic options available
- Glucose 6 phosphate dehydrogenase status normal
- ECOG performance status 0-2
- Normal creatinine and transaminase
- Women of child-bearing potential confirm negative pregnancy test
Exclusion
- Significant co-morbid disorders
- Significant psychiatric symptoms
- Smoking
- Excessive alcohol or drug use
- Enrollment in other experimental therapy
- Active infection
- Patients experiencing ongoing response to recent treatments
- Patients who have received chemotherapy within 30 days or biological therapy within 6 weeks
Key Trial Info
Start Date :
February 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2011
Estimated Enrollment :
2 Patients enrolled
Trial Details
Trial ID
NCT00626444
Start Date
February 1 2008
End Date
December 1 2011
Last Update
May 16 2025
Active Locations (1)
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1
Jefferson-Myrna Brind Center of Integrative Medicine
Philadelphia, Pennsylvania, United States, 19107