Status:
COMPLETED
Randomised Controlled Trial of Electroconvulsive Therapy (ECT) in Relapse Prevention of Depression
Lead Sponsor:
Örebro County Council
Collaborating Sponsors:
Uppsala-Örebro Regional Research Council
Conditions:
Depressive Disorder, Major
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The purpose of the study is to determine if continuation electroconvulsive therapy (ECT) is safe and effective in relapse prevention of depression.
Detailed Description
Randomized multicenter clinical trial with two parallel groups. Patients with major depression (unipolar or bipolar), who have remitted with electroconvulsive therapy (ECT) are eligible. All patients ...
Eligibility Criteria
Inclusion
- MINI-PLUS verified major depressive episode (unipolar or bipolar).
- ECT within the last 3 weeks.
- Either Remission defined as MADRS \< 10 or
- Response defined as MADRS \< 15 combined with patient assessed CGI-I of at least much improved
Exclusion
- Schizophrenia or Schizoaffective disorder
- Addiction or Dependence
- Kidney disease that contraindicates lithium treatment
- Vascular or heart disease that contraindicates venlafaxine treatment
- Uncontrolled Epilepsia
- Age less that 18
- Pregnancy or Lactation
Key Trial Info
Start Date :
January 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2012
Estimated Enrollment :
56 Patients enrolled
Trial Details
Trial ID
NCT00627887
Start Date
January 1 2008
End Date
May 1 2012
Last Update
June 22 2012
Active Locations (4)
Enter a location and click search to find clinical trials sorted by distance.
1
Psychiatric Clinic
Säter, Dalarna County, Sweden, 78327
2
Löwenströmska sjukhuset
Stockholm, Stockholm County, Sweden, 11000
3
Psychiatric Clinic
Uppsala, Uppsala County, Sweden, 75017
4
Psychiatric clinic
Örebro, Örebro County, Sweden, 70116