Status:
COMPLETED
Intracoronary Infusion of Autologous Bone Marrow Cells for Treatment of Idiopathic Dilated Cardiomyopathy
Lead Sponsor:
Fundación Pública Andaluza Progreso y Salud
Collaborating Sponsors:
Iniciativa Andaluza en Terapias Avanzadas
Conditions:
Dilated Cardiomyopathy
Eligibility:
All Genders
18-80 years
Phase:
PHASE2
Brief Summary
The main aim of the study is to determine whether intracoronary infusion of autologous bone marrow mononuclear cells can improve the ventricular function of patients with idiopathic dilated cardiomyop...
Detailed Description
Clinical studies have shown that bone marrow cells can regenerate damaged myocardium after ischemic cardiopathy; however scarce information is available from patients with non-ischemic dilated cardiom...
Eligibility Criteria
Inclusion
- Patients of both genders with established clinical and angiographic diagnosis of Idiopathic Dilated Cardiomyopathy who accept to participate in the trial.
- They should have symptoms and/or signs of heart failure, despite optimized medical treatment.
- Angiographic ejection fraction should be less than 50%.
Exclusion
- Associated coronary artery disease.
- Any history or suspicion of a toxic, pharmacologic or deposit etiology.
- Absence of resynchronization therapy.
- Age longer than 80 years.
- Associated malignant or pre-malignant systemic disease.
- Associated hematologic disorder.
Key Trial Info
Start Date :
February 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2010
Estimated Enrollment :
27 Patients enrolled
Trial Details
Trial ID
NCT00629096
Start Date
February 1 2008
End Date
December 1 2010
Last Update
December 5 2014
Active Locations (1)
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1
Reina Sofía University Hospital
Córdoba, Córdoba, Spain, 14004