Status:

COMPLETED

Effect of Celecoxib Versus Placebo Before and After Knee Surgery on the Overall Use of Analgesics After Surgery

Lead Sponsor:

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

Conditions:

Arthroscopy

Eligibility:

All Genders

18-65 years

Phase:

PHASE4

Brief Summary

To compare the total analgesic use at 24 hours after arthroscopic knee surgery in patients treated with celecoxib versus placebo.

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Diagnosed knee meniscus pathology requiring ambulatory arthroscopic meniscectomy or partial meniscectomy
  • Willing to participate in study for 36 hours and come to follow-up visit 7 days post-surgery
  • Exclusion criteria:
  • Osteoarthritis, inflammatory arthritis, or previous fracture of index joint
  • Received acetaminophen or low-dose narcotic within 8 hours of surgery
  • Have received oral (4 weeks), intramuscular (2 months), intra-articular (3 months) or soft-tissue (2 months) injections of corticosteroids of the first dose of study medication or received intra-articular injections of hyaluronic acid in the index joint within 9 months of the first dose of study medication

Exclusion

    Key Trial Info

    Start Date :

    February 1 2003

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    August 1 2003

    Estimated Enrollment :

    200 Patients enrolled

    Trial Details

    Trial ID

    NCT00633386

    Start Date

    February 1 2003

    End Date

    August 1 2003

    Last Update

    February 21 2021

    Active Locations (9)

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    Page 1 of 3 (9 locations)

    1

    Pfizer Investigational Site

    Phoenix, Arizona, United States, 85023

    2

    Pfizer Investigational Site

    St. Petersburg, Florida, United States, 33713

    3

    Pfizer Investigational Site

    Baltimore, Maryland, United States, 21218

    4

    Pfizer Investigational Site

    Springfield, Massachusetts, United States, 01199