Status:

TERMINATED

Study Evaluating 2 Dosing Regimens Of TRU-015 In Rheumatoid Arthritis

Lead Sponsor:

Pfizer

Collaborating Sponsors:

Trubion Pharmaceuticals/Emergent BioSolutions Inc.

Conditions:

Arthritis, Rheumatoid

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

This study will evaluate the efficacy and safety of two dosing regimens of a compound known as TRU-015 in combination with methotrexate (MTX) in patients with active rheumatoid arthritis.

Eligibility Criteria

Inclusion

  • Clinical diagnosis of active seropositive rheumatoid arthritis on a stable dose of methotrexate (7.5-25 mg weekly) for at least 12 weeks with or without a history of anti-TNF use.

Exclusion

  • Any prior use of rituximab or other B cell depleting agents.
  • Any significant health problem other than rheumatoid arthritis
  • Clinically significant laboratory abnormalities

Key Trial Info

Start Date :

March 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2012

Estimated Enrollment :

222 Patients enrolled

Trial Details

Trial ID

NCT00634933

Start Date

March 1 2008

End Date

October 1 2012

Last Update

March 11 2013

Active Locations (65)

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Page 1 of 17 (65 locations)

1

Pfizer Investigational Site

Birmingham, Alabama, United States, 35294-7201

2

Pfizer Investigational Site

Paradise Valley, Arizona, United States, 85253

3

Pfizer Investigational Site

Los Angeles, California, United States, 90048

4

Pfizer Investigational Site

Los Angeles, California, United States, 90095

Study Evaluating 2 Dosing Regimens Of TRU-015 In Rheumatoid Arthritis | DecenTrialz