Status:
COMPLETED
Administration of GnRH Antagonist to Oocyte Donation Recipients
Lead Sponsor:
Centro Ginecologia y Obstetricia.
Collaborating Sponsors:
University of Valencia
Conditions:
Pregnancy
Embryo Implantation
Eligibility:
FEMALE
18-34 years
Brief Summary
This prospective and randomized study was performed to evaluate whether the replacement of GnRH agonist by a GnRH antagonist in oocyte donation recipients during endometrial preparation has any impact...
Detailed Description
This was a prospective and randomized study undertaken between January 2004 and December 2007. One hundred patients with an indication for oocyte donation with functioning ovaries and IVF with or with...
Eligibility Criteria
Inclusion
- Age between 18-34 years
- Body mass index between 19-30 kg/m2;
- History of regular menstrual cycles, ranging from 25-35 days
- No relevant systemic disease (all patients were screened for hepatitis B and C, human immunodeficiency viruses I and II, syphylis, and vaginal infection), genetic disease, severe endometriosis or pelvic inflamatory disease
- No more than two previous IVF cycles; and
- No previous IVF cycles with poor response (less than three oocytes in a previous IVF cycle) or severe ovarian hyperstimulation syndrome.
Exclusion
- Patients without inclusion criteria.
Key Trial Info
Start Date :
January 1 2004
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2007
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00635258
Start Date
January 1 2004
End Date
December 1 2007
Last Update
March 13 2008
Active Locations (1)
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1
CEGIOB
Valencia, Valencia, Spain, 46004