Status:

WITHDRAWN

Inter-Assay Growth Hormone and IGF-I Variability

Lead Sponsor:

Cedars-Sinai Medical Center

Conditions:

Acromegaly

Growth Hormone Deficiency

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to demonstrate the degree of variability in commercially available assays for Growth Hormone measurement in the context of clinical decision making for Growth Hormone (GH)...

Detailed Description

This research will explore the variability of GH and IGF-1 measurements by commercially available tests. The hypothesis is that the variability in GH and IGF-1 measurement will be sizable enough that ...

Eligibility Criteria

Inclusion

  • Male or Female age 18+
  • Clinical indication for testing GH response to secretagogue testing to evaluate for GHD OR clinical indication for testing for GH response to oral glucose load (75grams of glucose) to evaluate for Acromegaly either for diagnosis OR normal volunteer for control group.
  • Normal volunteers will be screened for evidence of pituitary endocrine dysfunction prior to Oral Glucose Tolerance Testing (OGTT) and Growth Hormone Releasing Hormone - Arginine Testing (GHRH-ARG).
  • Able to provide informed consent

Exclusion

  • Subjects taking GH
  • Pregnant or breast feeding

Key Trial Info

Start Date :

November 1 2007

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2011

Estimated Enrollment :

171 Patients enrolled

Trial Details

Trial ID

NCT00638287

Start Date

November 1 2007

End Date

January 1 2011

Last Update

October 6 2008

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