Status:
TERMINATED
Doubling the Maintenance Dose of Clopidogrel in Patients With High On-Clopidogrel Platelet Reactivity
Lead Sponsor:
University of Pecs
Conditions:
Stable Angina Pectoris
Ad Hoc Percutaneous Coronary Intervention
Eligibility:
All Genders
35-75 years
Phase:
PHASE3
Brief Summary
The purpose of the study is to determine whether administration of 150 mg clopidogrel is effective in reducing the one-year incidence of thromboischemic events in patients with high on-clopidogrel pla...
Eligibility Criteria
Inclusion
- Clopidogrel-naïve stable angina pectoris (CCS I-III)
- Coronary angiography that reveals significant DE NOVO coronary stenosis (diameter stenosis greater than 50% in two independent projections) feasible for ad hoc stent implantation
Exclusion
- Acute coronary syndrome (STEMI, NSTEMI or unstable angina)
- Administration of clopidogrel/ticlopidine/coumarin in the past 6 weeks
- Contraindication to antiplatelet therapy
- Significant LM stenosis
- PCI due to instent restenosis
- Lesion located in bypass grafts
- Stroke in past one year
- Reduced life expectancy
Key Trial Info
Start Date :
March 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2010
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT00638326
Start Date
March 1 2008
End Date
March 1 2010
Last Update
March 23 2010
Active Locations (1)
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1
Heart Institute, University of Pécs, Dept. of Interventional Cardiology
Pécs, Hungary, 7624