Status:

COMPLETED

Phenylephrine in Septic Shock

Lead Sponsor:

University of Roma La Sapienza

Conditions:

Septic Shock

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

The present study was conducted as a prospective, randomized, controlled study to compare: * the effects of norepinephrine and phenylephrine on systemic and regional hemodynamics in patients with cat...

Detailed Description

Thirty two septic shock patients requiring vasopressor support to maintain mean arterial pressure between 65 and 75 mmHg despite adequate volume resuscitation will be enrolled in the study. Patients w...

Eligibility Criteria

Inclusion

  • Clinical diagnosis of Septic shock
  • Vasopressor support to maintain mean arterial pressure (MAP) between 65 and 75 mmHg despite adequate volume resuscitation (pulmonary artery occlusion pressure = 13-18 mmHg and central venous pressure = 8-12 mmHg)

Exclusion

  • Pregnancy
  • Age \< 18 years
  • Present cardiac dysfunction
  • Present or suspected acute mesenteric ischemia

Key Trial Info

Start Date :

November 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2008

Estimated Enrollment :

32 Patients enrolled

Trial Details

Trial ID

NCT00639015

Start Date

November 1 2007

End Date

June 1 2008

Last Update

October 26 2017

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Departement of Anesthesiology and Intensive Care of the University of Rome "La Sapienza" Viale del Policlinico 155

Rome, Italy, 00161