Status:
COMPLETED
Effects of Hydration to Prevent Contrast Induced Nephropathy in PCI for ST-elevation Myocardial Infarction.
Lead Sponsor:
Azienda USL Reggio Emilia - IRCCS
Collaborating Sponsors:
Azienda Sanitaria Ospedaliera
Conditions:
Contrast Induced Nephropathy
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The aim of the study is to test the efficacy of low versus high volume hydration and two different solutions (sodium chloride versus sodium bicarbonate) in preventing contrast induced nephropathy (CIN...
Detailed Description
Contrast-induced nephropathy (CIN) is associated with increased morbidity and mortality after percutaneous coronary interventions (PCI). Patients with ST elevation myocardial infarction (STEMI) are at...
Eligibility Criteria
Inclusion
- Age \> 18 years of years
- Chest pain lasting at least 30 minutes, non responsive to nitrates, associated to ST elevation of at least 0.2 mV on surface ECG in two or more contiguous leads or to new left bundle branch block.
- Informed consent
Exclusion
- Chronic hemodialytic or peritoneal treatment
- Coronary anatomy unsuitable for PCI
- Need of emergency coronary artery by-pass grafting
- Post-anoxic coma
- Pregnancy
Key Trial Info
Start Date :
June 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2010
Estimated Enrollment :
599 Patients enrolled
Trial Details
Trial ID
NCT00639912
Start Date
June 1 2007
End Date
October 1 2010
Last Update
June 11 2025
Active Locations (5)
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1
Azienda Ospedaliera Universitaria S. Anna
Ferrara, Emilia-Romagna, Italy
2
Nuovo Ospedale Civile di Baggiovara
Modena, Emilia-Romagna, Italy, 41100
3
Arcispedale S. Maria Nuova
Reggio Emilia, Emilia-Romagna, Italy, 42100
4
Dipartimento di Cardiologia, Ospedale di Lavagna
Lavagna, Genova, Italy, 16033