Status:
UNKNOWN
Respiratory Mechanics in Brain Injured Patients
Lead Sponsor:
Università degli Studi dell'Insubria
Conditions:
Brain Injury
Acute Lung Injury
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The hypothesis is that brain injury patients have alterations of the respiratory system related to intraabdominal pressure. Furthermore application of moderate levels of PEEP may improve respiratory f...
Detailed Description
We investigate the mechanical properties of the respiratory system, partitioned into its lung and chest wall components, the functional residual capacity, the gas-exchange and alveolar recruitment in ...
Eligibility Criteria
Inclusion
- Male and Female
- Age \> 18 yrs
- Mechanical ventilation
- No smoker
- No lung injury at entry
- Brain injury (traumatic or postoperative or spontaneous bleeding) in brain injury group
Exclusion
- Pregnancy
- Hemodynamic instability
- Immunodepression
Key Trial Info
Start Date :
June 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2008
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00639990
Start Date
June 1 2007
End Date
December 1 2008
Last Update
March 20 2008
Active Locations (1)
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1
Ospedale di Circolo e Fondazione Macchi
Varese, Varese, Italy, 21100