Status:

COMPLETED

Safety and Tolerability Study of ABT-089 in Children With Attention-Deficit/Hyperactivity Disorder (ADHD)

Lead Sponsor:

AbbVie (prior sponsor, Abbott)

Conditions:

Attention-Deficit/Hyperactivity Disorder

Eligibility:

All Genders

6-12 years

Phase:

PHASE2

Brief Summary

The purpose of this study is to test if the investigational medication ABT-089 is a safe and effective treatment for children with Attention Deficit Hyperactivity Disorder (ADHD).

Eligibility Criteria

Inclusion

  • Have voluntarily signed an informed consent form.
  • Meet diagnostic criteria for attention-deficit/hyperactivity disorder (ADHD) based on detailed evaluation and interview with parent(s).
  • Subject is generally in good health based on medical history, physical examination, clinical lab tests and ECG.
  • Subject weights at least 37 pounds (17 kg)
  • Female subjects of child-bearing potential must have a negative urine pregnancy test at screening and baseline and agree to comply with applicable contraceptive requirements.
  • Subject can swallow pills and subjects and parents are able to keep required appointments for clinic visits and all tests, including blood draws and examinations.

Exclusion

  • Subject has a current or past diagnosis of bipolar disorder, psychosis, autism, Asperger syndrome, pervasive developmental disorder, tics, Tourette syndrome, mental retardation, seizure disorder or traumatic brain injury.
  • Current diagnosis of obsessive-compulsive disorder, eating disorder, anxiety disorder or depressive disorder requiring treatment of any kind.
  • Subject has a history of, or ongoing, serious medical problem.
  • Subject has a history of significant allergic reaction to any drug.
  • Subject is planning to begin any type of behavioral or psychotherapy for treatment of ADHD.
  • Subject requires ongoing treatment with any psychiatric medication.

Key Trial Info

Start Date :

March 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2008

Estimated Enrollment :

121 Patients enrolled

Trial Details

Trial ID

NCT00640419

Start Date

March 1 2008

End Date

July 1 2008

Last Update

January 18 2013

Active Locations (13)

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Page 1 of 4 (13 locations)

1

Site Reference ID/Investigator# 7536

Little Rock, Arkansas, United States, 72205

2

Site Reference ID/Investigator# 7954

Bradenton, Florida, United States, 34208

3

Site Reference ID/Investigator# 7543

Jacksonville, Florida, United States, 32216

4

Site Reference ID/Investigator# 7542

Orlando, Florida, United States, 32806