Status:

COMPLETED

A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Levofloxacin for the Treatment of Mild to Moderate Pneumonia in Adult Patients

Lead Sponsor:

Pfizer

Conditions:

Pneumonia

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The study was performed to see if a single, 2.0-g oral dose of azithromycin sustained release (SR) was at least as effective as a 7-day regimen of levofloxacin (500 mg once daily) for the treatment of...

Eligibility Criteria

Inclusion

  • Patients with clinical evidence of mild to moderate community-acquired pneumonia, including cough productive of sputum and a diagnosis of pneumonia, were included.

Exclusion

  • Key exclusion criteria were treatment with any systemic antibiotic of greater than one dose or one combination dose within the previous 7 days, previously diagnosed conditions which tend to mimic or complicate the course and the evaluation of the evaluation process (e.g., bronchiectasis, lung abscess or empyema, active tuberculosis, pulmonary malignancy, cystic fibrosis, post-obstructive pneumonia), hospitalization in the previous 14 days or infection acquired in the hospital, and residents of a long-term care facility.

Key Trial Info

Start Date :

April 1 2003

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2004

Estimated Enrollment :

468 Patients enrolled

Trial Details

Trial ID

NCT00643734

Start Date

April 1 2003

End Date

April 1 2004

Last Update

March 26 2008

Active Locations (65)

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Page 1 of 17 (65 locations)

1

Pfizer Investigational Site

Mesa, Arizona, United States, 85206

2

Pfizer Investigational Site

Phoenix, Arizona, United States, 85014

3

Pfizer Investigational Site

San Luis Obispo, California, United States, 93401

4

Pfizer Investigational Site

San Mateo, California, United States, 94403

A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Levofloxacin for the Treatment of Mild to Moderate Pneumonia in Adult Patients | DecenTrialz