Status:

COMPLETED

Clinical Use of an Absorbable Coated Suture Material in Surgery (Safil)

Lead Sponsor:

Aesculap AG

Conditions:

Gastrointestinal Diseases

Laparotomy

Eligibility:

All Genders

18-80 years

Phase:

PHASE4

Brief Summary

The purpose is to test a coated polyglycolic acid multifilament suture in gastrointestinal surgery as part of a controlled randomized single blinded parallel group trial. The applicability and safety ...

Eligibility Criteria

Inclusion

  • Patients of both sexes, undergoing a gastrointestinal hand made one-layer running (A) or two-layer (B) anastomotic procedure where the use of synthetic absorbable surgical suture material is indicated.
  • Written consent to participate in the study

Exclusion

  • Emergency patients that cannot be properly informed about the clinical trial and cannot give their written consent
  • Pregnancy or lactation period
  • Patients suffering from a diffuse purulent peritonitis or generalized diseases, which can have consequences for the healing of the asnastomosis (e.g. ubalanced diabetes, progressed uremia, massive hypoproteinaemia, sever jaundice, generalized intraabdominal tumor metastases, severe tumorous cachexia, severe avitaminosis, chronic liver disease.
  • Patients who are undergoing a therapeutic procedure, which can have consequences for the healing of the anastomosis (e.g. treatment with corticosteroids or cytostatics, local radiation in the operating area)
  • Laparoscopial Procedures
  • Patients who are not willing to cooperate and legally incapacitated people

Key Trial Info

Start Date :

April 1 1998

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2002

Estimated Enrollment :

210 Patients enrolled

Trial Details

Trial ID

NCT00645684

Start Date

April 1 1998

End Date

May 1 2002

Last Update

March 28 2008

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Bugat Pal Korhaz, Sebeszeti Osztaly

Gyöngyös, Hungary

2

B.-A.-Z. Megyei Korhaz, Sebeszeti Osztaly

Miskolc, Hungary

3

Medical School of University Pecs

Pécs, Hungary