Status:

COMPLETED

Study of the Safety and Efficacy of the Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects With Moderately to Severely Active Psoriatic Arthritis

Lead Sponsor:

Abbott

Conditions:

Arthritis

Psoriatic

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

Multicenter Study of the Safety and Efficacy of the Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects with Moderately to Severely Active Psoriatic Arthritis

Eligibility Criteria

Inclusion

  • Moderate to severe PsA
  • Inadequate response to DMARD therapy
  • Corticosteroid stable dose \<= 10 mg QD
  • DMARDs must have been taken for 3 months and stable dose for 4 weeks
  • MTX maximum dose = \<= 30 mg/week
  • Active chronic plaque PS or documented history of chronic plaque PS

Exclusion

  • No other active skin disease

Key Trial Info

Start Date :

March 1 2003

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

315 Patients enrolled

Trial Details

Trial ID

NCT00646386

Start Date

March 1 2003

Last Update

March 28 2008

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