Status:
COMPLETED
Genetics and Markers of Degenerative and Inflammatory Eye Diseases
Lead Sponsor:
National Eye Institute (NEI)
Conditions:
Diabetic Retinopathy
Age-Related Macular Degeneration (AMD)
Eligibility:
All Genders
4+ years
Brief Summary
This study will identify genes that are associated with inflammation or degeneration of the retina (membrane lining the back of the eye that relays vision signals to the brain). It is thought that man...
Detailed Description
Objective: This project will study epigenetic mechanisms, the inheritance of (both Mendelian and complex) and biomarkers of Immune Mediated Eye Diseases, in families of many nationalities and ethnic ...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Participants with the following will be recruited:
- Individuals or family members of individuals with immune mediated retinal disorders, including uveitis, age related macular degeneration, and diabetic retinopathy.
- Adults must be capable of providing their own consent.
- All participants must be able to cooperate with study examination and phlebotomy.
- Children must be older than 4 years of age.
- EXCLUSION CRITERIA:
- Individuals with diseases, infections, or trauma that mimic immune medicated retinal disorders.
- Children requiring sedation for study procedures.
Exclusion
Key Trial Info
Start Date :
March 27 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 4 2018
Estimated Enrollment :
609 Patients enrolled
Trial Details
Trial ID
NCT00647439
Start Date
March 27 2008
End Date
December 4 2018
Last Update
December 10 2018
Active Locations (1)
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1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892