Status:
TERMINATED
Study of Oral Dehydroepiandrosterone(DHEA) to Treat Previously Unexplained Infertility
Lead Sponsor:
Center for Human Reproduction
Conditions:
Primary Ovarian Insufficiency
Unexplained Infertility
Eligibility:
FEMALE
21-37 years
Phase:
PHASE2
PHASE3
Brief Summary
The experimental focus of this project is on the interaction of DHEA treatment on pregnancy in women with otherwise unexplained infertility and evidence of premature ovarian aging (POA).
Detailed Description
Recruitment: Eligible patients will be recruited by advertising on the web and in newspaper. We will screen women under 38 years old with regular menstrual cycles and more than one year of infertilit...
Eligibility Criteria
Inclusion
- \>= 1 year of infertility
- \< 38 years old
- Normal HSG
- Normal Semen analysis (Count \>= 20 million/ motility \> 50%/ Kruger morph \> 14%.
- Regular menses
- Willingness to sign informed consent for study randomization
- Willingness to participate in 8 months of non-IVF will he him treatment.
Exclusion
- Abnormal semen analysis
- Abnormal HSG
- Baseline FSH/E2 within normal age specific criteria
- Medical condition that would contraindicate pregnancy, ovulation induction or general anesthesia
- Family history of significant genetic disease, or factor V leiden thrombophilia
- Inability to present for monitoring visits
- Inability to follow medication instruction
- Desire to undergo other fertility treatments before completing eight months of this trial
Key Trial Info
Start Date :
March 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2014
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT00650754
Start Date
March 1 2008
End Date
March 1 2014
Last Update
September 30 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Center for Human Reproduction
New York, New York, United States, 10021