Status:

COMPLETED

Endoscopic Ultrasound Compared With Pancreatic Function Testing for Diagnosis of Chronic Pancreatitis

Lead Sponsor:

The Cleveland Clinic

Collaborating Sponsors:

ChiRhoClin, Inc.

The National Pancreas Foundation

Conditions:

Chronic Pancreatitis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This is a investigator-initiated, single-center, prospective study to evaluate endoscopic ultrasound (EUS) as a diagnostic test for chronic pancreatitis (CP). EUS detects abnormalities of the pancreas...

Eligibility Criteria

Inclusion

  • Male or female, age greater than 18 years.
  • Capable of informed consent.
  • If female and not more than 1 year post-menopausal, or surgically sterile, must use medically accepted form of contraception or abstain from sexual activities during study.
  • EUS and CCK ePFT planned for a structural evaluation of the pancreas in patients with pancreatitis or pancreatic-type abdominal pain.

Exclusion

  • Severe cardiac disease (stable or unstable angina, congestive heart failure, uncontrolled arrhythmias, implantable defibrillator, severe valvular disease, etc.).
  • Severe pulmonary disease (Severe asthma, COPD or interstitial lung disease requiring nebulizer treatment or home oxygen, pulmonary hypertension).
  • Severe renal disease (history of chronic renal insufficiency \[creatinine \>2.0\] or chronic hemodialysis).
  • Inability to undergo conscious sedation or general anesthesia.
  • Ongoing illicit drug use or abuse. Must be drug free for \>1 year.
  • Acute pancreatitis within the past 2 months.
  • Prior pancreatic surgery.

Key Trial Info

Start Date :

May 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2007

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT00651053

Start Date

May 1 2005

End Date

December 1 2007

Last Update

February 3 2016

Active Locations (1)

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Cleveland Clinic Foundation

Cleveland, Ohio, United States, 44195