Status:
TERMINATED
Predictive Blood Tests for Severe Radiation Reactions in Breast Cancer Patients
Lead Sponsor:
State University of New York - Upstate Medical University
Collaborating Sponsors:
Carol M. Baldwin Breast Cancer Research Fund, Inc.
Conditions:
Abnormalities, Radiation-Induced
Eligibility:
FEMALE
48+ years
Brief Summary
Some patients who undergo breast cancer treatment with lumpectomy followed by radiation therapy develop significant late skin and soft tissue changes, resulting in a poor cosmetic outcome. The goal of...
Detailed Description
Three tubes of blood will be drawn from each subject. Two members of the study team will also independently assess each subject for the degree to which various radiation-induced soft tissue changes ar...
Eligibility Criteria
Inclusion
- Breast cancer treatment: lumpectomy followed by external beam XRT to breast
- Age at the time of radiotherapy treatment: 45-65 years old
- XRT dose to breast: \>/= 4500 and \</= 5200 cGy, fraction size 180 or 200 cGy
- Dose distribution: no area receiving \>/= 112% of prescribed dose
- Follow-ups: patients must be \>/= 2.5 years post-treatment
Exclusion
- Reconstructive surgery to involved breast
Key Trial Info
Start Date :
August 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2012
Estimated Enrollment :
38 Patients enrolled
Trial Details
Trial ID
NCT00652678
Start Date
August 1 2006
End Date
August 1 2012
Last Update
October 22 2021
Active Locations (1)
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1
SUNY Upstate Medical University
Syracuse, New York, United States, 13210