Status:

UNKNOWN

Influence of Glucagon Inhibition in Relation to the Anti-Diabetic Effect of Glucagon-Like Peptide-1 (GLP-1) in Patients With Type 2 Diabetes Mellitus

Lead Sponsor:

University Hospital, Gentofte, Copenhagen

Collaborating Sponsors:

University of Copenhagen

Hvidovre University Hospital

Conditions:

Type 2 Diabetes Mellitus

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

Incretinbased treatment of patients with type 2 diabetes mellitus (T2DM) has increasing interest. The incretin glucagon-like peptide-1 (GLP-1) stimulates beta-cells to increased secretion and producti...

Eligibility Criteria

Inclusion

  • Type 2 Diabetes Mellitus according to criteria from WHO
  • Normal hepatic and kidney function
  • No overt diabetic complications
  • Treatment with insulin or glitazones
  • Informed consent

Exclusion

  • BMI \< 23
  • BMI \> 35
  • HbA1c \> 10%
  • Pregnancy

Key Trial Info

Start Date :

March 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2009

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT00655603

Start Date

March 1 2008

End Date

September 1 2009

Last Update

April 6 2009

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