Status:
UNKNOWN
Magnetic Resonance (MR) Spectroscopy In Familial Mediterranean Fever (FMF) Patients
Lead Sponsor:
Sheba Medical Center
Conditions:
Familial Mediterranean Fever
Eligibility:
All Genders
18-45 years
Brief Summary
Familial Mediterranean fever (FMF) is an inherited disorder of unknown etiology, characterized by recurrent episodes of fever, peritonitis and/or pleuritis. Fever is the cardinal manifestation of FMF...
Eligibility Criteria
Inclusion
- Fulfilling the Tel Hashomer criteria for the diagnosis of FMF \[5\].
- Suffering from episodes of exertional leg pain and or exertional ankle edema
- 18-45 years old
- On a stable (≥ 2 weeks) dose of oral colchicine therapy
- Non-smokers
Exclusion
- with known peripheral vascular disease (PVD) and/or multiple risk factors for PVD (such as diabetes, hypertension, hyperlipidemia)
- Suffering from muscular or neurological diseases not related to FMF
- With elevated serum creatinine / liver enzymes/ creatine phosphokinase (CPK) levels.
- Suffering from claustrophobia, or with metal fragments in body tissue, or with other contraindications for MRI.
Key Trial Info
Start Date :
September 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00658060
Start Date
September 1 2007
Last Update
April 14 2008
Active Locations (1)
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1
Sheba Medical Center
Ramat Gan, Israel, 52621