Status:
COMPLETED
The Effects of Repetitive Transcranial Magnetic Stimulation in Healthy Human Subjects
Lead Sponsor:
Centre for Addiction and Mental Health
Conditions:
Healthy
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
It has been suggested that the therapeutic effects of repetitive transcranial magnetic stimulation (rTMS) are mediated through changes in cortical inhibition (CI). However, in healthy subjects the eff...
Detailed Description
It has been demonstrated that several neurologic and psychiatry disorders are associated with dysfunctional cortical inhibitory mechanisms and alterations in neurotrophins (biological markers involved...
Eligibility Criteria
Inclusion
- are voluntary and competent to consent
- between the ages of 18-65
- considered a healthy individual free of psychopathology based on the Personality Assessment Inventory
- right-handed determined by the TMS-screener and demographic form
- self-reported non-smoker
- do not have a self-reported concomitant major medical or neurologic illness
- women in childbearing years will be recruited only if they are on an effective means of birth control determined through completion of the TMS screener and demographic form.
Exclusion
- demonstrate a failure to tolerate the procedure
- develop any significant adverse events (e.g., seizure or seizure-like activity)
- withdraw consent
- the principal investigator believes that for safety reasons it is in the best interest of the individual to be withdrawn
Key Trial Info
Start Date :
April 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2014
Estimated Enrollment :
56 Patients enrolled
Trial Details
Trial ID
NCT00658307
Start Date
April 1 2008
End Date
May 1 2014
Last Update
May 2 2014
Active Locations (1)
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1
Centre for Addiction and Mental Health
Toronto, Ontario, Canada, M6J 1H4