Status:

COMPLETED

Target Site Pharmacokinetics of Ertapenem After Multiple Doses in Diabetes Patients With Soft Tissue Infection

Lead Sponsor:

Medical University of Vienna

Conditions:

Soft Tissue Infection

Eligibility:

All Genders

18-85 years

Phase:

PHASE4

Brief Summary

Background/rationale: Ertapenem is an innovative antimicrobial agent, which is approved in the European Union for diabetic foot infections of the skin and soft tissue. Although its antimicrobial spect...

Eligibility Criteria

Inclusion

  • Male or female, aged between 18 and 85 years
  • Diagnosis of Diabetes mellitus
  • Clinically diagnosed skin or soft tissue infection and/or infected ulcers of the leg, requiring antimicrobial therapy
  • Prescription of ertapenem for therapeutic reasons
  • Willingness and ability to comply with the protocol
  • Signed informed consent

Exclusion

  • HIV, Hepatitis B or C positive
  • Allergy or hypersensitivity against study drug
  • Severe renal impairment, defined by a serum creatinine level \> 1.6 mg/L
  • Pregnancy, or women of child bearing potential not willing to apply adequate contraception during study period
  • Any disease considered relevant for proper performance of the study, or risks to the patient, at the discretion of the investigator

Key Trial Info

Start Date :

February 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2011

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT00658866

Start Date

February 1 2008

End Date

February 1 2011

Last Update

August 9 2011

Active Locations (1)

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1

Medical University Vienna, Department of Clinical Pharacology

Vienna, Vienna, Austria, 1090