Status:
COMPLETED
Effects of Leptin Replacement in Children
Lead Sponsor:
University of Miami
Collaborating Sponsors:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Obesity
Metabolic Syndrome
Eligibility:
MALE
5-18 years
Phase:
PHASE2
Brief Summary
To assess the endocrine and immune effects of leptin replacement in leptin-deficient children, from a consanguineous family. The hypothesis is that leptin replacement will have significant effects on ...
Detailed Description
The proposed study of the treatment of a child with congenital leptin deficiency will permit to elucidate key aspects of human endocrine function, and will give new insights on the role of leptin in h...
Eligibility Criteria
Inclusion
- Children with a functional leptin gene mutation from a consanguineous Turkish family. Only one leptin-naïve child from this family is alive and eligible.
Exclusion
- N/A
Key Trial Info
Start Date :
June 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 16 2010
Estimated Enrollment :
1 Patients enrolled
Trial Details
Trial ID
NCT00659828
Start Date
June 1 2005
End Date
April 16 2010
Last Update
February 13 2020
Active Locations (1)
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1
University of Miami, Center on Pharmacogenomics
Miami, Florida, United States, 33132