Status:

COMPLETED

Investigation of Efficacy and Safety of Botulinum Toxin A (Botox-Allergan Inc) in Migraine Headaches

Lead Sponsor:

Yale University

Conditions:

Refractory Migraine

Eligibility:

All Genders

18+ years

Phase:

PHASE2

PHASE3

Brief Summary

The hypothesis of this study is that injection of botulinum toxin A into the muscles around the head (frontal, temporal, posterior neck, occipital) can reduce the intensity and frequency of migraine h...

Detailed Description

Contact PI for study details

Eligibility Criteria

Inclusion

  • Adults 18 and older
  • Migraine for more than three months, that fail to respond to two or more major anti-migraine drug, meeting criteria of chronic migraine

Exclusion

  • Age below 18
  • Pregnant or may become pregnant
  • Disease of neuromuscular junction or drugs that affect N-M junction
  • Allergy to Botox
  • Previous use of Botox for migraine by similar methodology

Key Trial Info

Start Date :

January 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2015

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT00660192

Start Date

January 1 2008

End Date

July 1 2015

Last Update

March 14 2016

Active Locations (1)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (1 locations)

1

Yale Physician's Building, 800 Howard Ave, lower level,

New Haven, Connecticut, United States, 06510