Status:

COMPLETED

Effect of Soy Isoflavones on Bone Mineral Density and Physical Performance Indices

Lead Sponsor:

Creighton University

Collaborating Sponsors:

Solae, LLC

Conditions:

Osteoporosis

Eligibility:

FEMALE

55-72 years

Phase:

NA

Brief Summary

The aim of the present study was to investigate the effects of soy and soy plus isoflavones on bone mineral Density and physical performance in post menopausal women.

Detailed Description

Post menopausal estrogen deficiency causes physiologic changes in body composition including decreased lean body weight and bone mass. A decrease in muscle strength along with osteoporosis puts post m...

Eligibility Criteria

Inclusion

  • at least 55-75 years of age
  • at least 7 years post menopausal either spontaneous or surgical

Exclusion

  • must not have used estrogen for atleast 2 months prior to entering study
  • must be on no bone active drugs such as bisphosphonates, anti convulsants, calcitonin and long term steroids
  • osteoporosis (T-score\<-2.5)
  • BMI \<18 or \>34

Key Trial Info

Start Date :

January 1 2001

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2004

Estimated Enrollment :

203 Patients enrolled

Trial Details

Trial ID

NCT00661856

Start Date

January 1 2001

End Date

January 1 2004

Last Update

April 21 2008

Active Locations (1)

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1

Creighton University Medical Center

Omaha, Nebraska, United States, 68131