Status:

COMPLETED

Pharmacokinetics and Pharmacodynamics of Fructose

Lead Sponsor:

University of Florida

Conditions:

Healthy

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to determine whether sucrose vs high fructose corn syrup from a soft drink results in differences in various metabolic byproducts such as fructose, glucose, serum uric aci...

Detailed Description

Fructose consumption has risen sharply during the past several decades. Since its introduction to the United States in 1967, high fructose corn syrup (HFCS) has overtaken sucrose as the main sweetener...

Eligibility Criteria

Inclusion

  • adult subjects aged 18 years or older
  • either gender
  • any ethnicity
  • willing to abstain from drinking any alcohol 3 days prior to a study visit

Exclusion

  • history of liver or kidney disease
  • history of diabetes mellitus or fasting blood glucose ≥ 126 mg/dl or random blood glucose ≥ 200 mg/dl
  • currently taking any medication (except oral contraceptives)
  • consume more than 1 alcoholic drink per day
  • pregnant or breast-feeding
  • blood donor in the previous 8 weeks
  • history of gout

Key Trial Info

Start Date :

March 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 1 2010

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT00661947

Start Date

March 1 2008

End Date

August 1 2010

Last Update

February 16 2012

Active Locations (1)

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1

University of Florida, Department of Pharmacy Practice, Center for Pharmacogenomics

Gainesville, Florida, United States, 32610