Status:

COMPLETED

Effects of Losartan on Insulin Resistance in Patients With Heart Failure

Lead Sponsor:

Tottori University Hospital

Conditions:

Heart Failure

Eligibility:

All Genders

Phase:

PHASE4

Brief Summary

The purpose of this study is to evaluate the effects of losartan, an ARB, on glucose metabolism and inflammatory cytokines in CHF patients treated with ACE inhibitors.

Detailed Description

Chronic heart failure (CHF) is associated with marked insulin resistance, characterized by both fasting and stimulated hyperinsulinemia. Furthermore, insulin resistance is a predictor of CHF and assoc...

Eligibility Criteria

Inclusion

  • chronic stable heart failure

Exclusion

  • renal dysfunction or under treatment with antidiabetic agents

Key Trial Info

Start Date :

April 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2007

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT00663377

Start Date

April 1 2006

End Date

March 1 2007

Last Update

April 22 2008

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