Status:
TERMINATED
Kidney Transplantation in Patients With Sickle Cell Disease
Lead Sponsor:
Emory University
Conditions:
Sickle Cell Disease
Eligibility:
All Genders
18-65 years
Brief Summary
The purpose of this research is to better characterize the components and mechanisms of the immune systems of persons with sickle cell disease who have had a kidney transplant and are immunosuppressed...
Detailed Description
Sickle cell disease is a common disease in the African-American population. In sickle cell disease red blood cells are abnormal in shape and can damage organs. In particular, patients with sickle cell...
Eligibility Criteria
Inclusion
- Male or female patients between 18 and 65 years of age
- Patients capable of understanding the purposes and risks of the study, who can give written informed consent and who are willing to participate in and comply with the study.
- Women of childbearing potential must have a negative serum pregnancy test within 7 days prior to enrollment and must not be breast-feeding.
- Patients must be diagnosed with Sickle Cell Disease (SS phenotype)
Exclusion
- Patients with any prior organ transplant or multi-organ transplant recipients.
- Patients with evidence of an active systemic infection requiring the continued use of antibiotics, evidence of an HIV infection, or the presence of a chronic active hepatitis B or C.
- Patients with history of malignancy in the last 5 years (except successfully treated localized non-melanotic skin cancer)
- Patients with active illegal drug use
Key Trial Info
Start Date :
March 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2010
Estimated Enrollment :
2 Patients enrolled
Trial Details
Trial ID
NCT00663507
Start Date
March 1 2008
End Date
December 1 2010
Last Update
February 27 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Mason Outpatient Tranplant Clinic Emory University
Atlanta, Georgia, United States, 30302