Status:
COMPLETED
Evaluating the Effects of Omega-3 Fatty Acids on Heart Disease and Behavior
Lead Sponsor:
University of Pittsburgh
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
National Center for Complementary and Integrative Health (NCCIH)
Conditions:
Cardiovascular Diseases
Mood Disorders
Eligibility:
All Genders
30-55 years
Phase:
NA
Brief Summary
Omega-3 fatty acids are a certain kind of fish fat that has recently been shown to have health benefits. This study will examine the effectiveness of fish oil supplementation for reducing the early si...
Detailed Description
Cardiovascular disease (CVD) is a broad term that includes diseases that affect the heart and blood vessels, including coronary heart disease, heart failure, high blood pressure, stroke and vascular d...
Eligibility Criteria
Inclusion
- Currently employed at least 25 hours a week, but does not regularly work the third shift (i.e., night shift)
- English is primary language
- Consumes less than 300 mg/day of long-chain omega-3 fatty acids.
Exclusion
- Serious allergy to fish (e.g., anaphylaxis, bronchospasm, serious skin reaction)
- History of atherosclerotic disease (e.g., myocardial infarction) or treatment of angina or claudication (e.g., angioplasty)
- Reported history of schizophrenia or bipolar disorder
- Long-term hepatitis
- Kidney failure
- Stroke or other neurological disorder
- Lung disease requiring drug treatment
- Stage 2 high blood pressure, defined as systolic blood pressure of 160 mm Hg or greater and diastolic blood pressure of 100 mm Hg or greater
- Alcohol consumption of more than five drinks per day each week (i.e., more than 35 alcoholic drinks each week)
- Pregnant or breastfeeding
- Currently taking any cardiovascular, psychotropic, glucocorticoid, lipid-lowering, insulin, or weight loss medications
- Currently taking fish oil supplements
Key Trial Info
Start Date :
June 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2012
Estimated Enrollment :
272 Patients enrolled
Trial Details
Trial ID
NCT00663871
Start Date
June 1 2008
End Date
October 1 2012
Last Update
June 11 2021
Active Locations (1)
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1
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15260