Status:

COMPLETED

Efficacy and Safety of T-817MA in Patients With Mild to Moderate Alzheimer's Disease

Lead Sponsor:

FUJIFILM Toyama Chemical Co., Ltd.

Conditions:

Alzheimer's Disease

Eligibility:

All Genders

50-90 years

Phase:

PHASE2

Brief Summary

The primary objective of the study is to evaluate the efficacy of T-817MA in AD patients to treat dementia. Efficacy will be cognitive function, as measured by the ADAS-cog cognitive assessment. The ...

Eligibility Criteria

Inclusion

  • Male or female (post-menopausal or surgically sterile)
  • Patients with Mild to moderate Alzheimer's disease who are receiving Donepezil.
  • Age 50 to 90 inclusive
  • Patients must be living in the community
  • Patients must have an eligible informant or study partner (caregiver)
  • Patients and eligible informant or study partner (caregiver) must be able to read and understand English.
  • Informed consent obtained from both the patient and the caregiver etc (According to the protocol)

Exclusion

  • Patients with clinically significant cardiac, hepatic or renal impairment
  • Patient have a dementia not of the Alzheimer's type etc (According to the protocol)
  • Patients who are taking any drug other than donepezil for Alzheimer's disease, including rivastigmine (Exelon®), galantamine (Razadyne®), memantine (Namenda™) or tacrine (Cognex®) taken within twelve (12) weeks of the Baseline Visit (Visit 2).

Key Trial Info

Start Date :

April 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2011

Estimated Enrollment :

373 Patients enrolled

Trial Details

Trial ID

NCT00663936

Start Date

April 1 2008

End Date

June 1 2011

Last Update

November 5 2013

Active Locations (35)

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Page 1 of 9 (35 locations)

1

Banner Alzheimer's Institute

Phoenix, Arizona, United States, 85006

2

Northwest NeuroSpecialists

Tucson, Arizona, United States, 85741

3

Collaborative Neuroscience Network, Inc.

Garden Grove, California, United States, 92845

4

Southwest Institute for Clinical Research, Inc.

Rancho Mirage, California, United States, 92270