Status:
COMPLETED
Ambulatory Continuous Peripheral Nerve Blocks for Treatment of Post-Amputation Phantom Limb and Stump Pain
Lead Sponsor:
University of California, San Diego
Collaborating Sponsors:
Summit Medical
National Institute of General Medical Sciences (NIGMS)
Conditions:
Amputation
Phantom Limb
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Research study to determine if putting local anesthetic-or numbing medication-through one or two tiny tube(s) placed next to the nerves that go to an amputated limb will decrease phantom limb and/or s...
Detailed Description
Specific Aim 1: To determine if, compared with current standard-of-care treatment, the addition of an ambulatory continuous peripheral nerve block decreases post-amputation phantom limb and stump pain...
Eligibility Criteria
Inclusion
- previous upper or lower limb amputation including at least one metacarpal or metatarsal bone, respectively
- age 18 years or older
- phantom limb and/or stump pain described as at least a 2 on the NRS for the previous week \[and pain occurring on a weekly basis over the previous month\]
- willing to have an ambulatory perineural infusion for 6 days
- willing to avoid additional "new" analgesic interventions from 4 weeks prior to at least 4 weeks following catheter placement, and preferably to 6 months following catheter placement
- the availability of a "caretaker" who will transport the subject home following the procedure and remain with the subject for the first night of the infusion
Exclusion
- known hepatic or renal insufficiency
- allergy to the study medications
- possessing a contraindication to perineural catheter placement or perineural local anesthetic infusion
Key Trial Info
Start Date :
October 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2011
Estimated Enrollment :
7 Patients enrolled
Trial Details
Trial ID
NCT00667264
Start Date
October 1 2008
End Date
December 1 2011
Last Update
June 28 2012
Active Locations (1)
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1
UCSD Medical Center
San Diego, California, United States, 92103