Status:

TERMINATED

Long Term Minor Sibling Donor Well-Being

Lead Sponsor:

M.D. Anderson Cancer Center

Conditions:

Disorder Related to Bone Marrow Transplantation

Blood Stem Cell Transplant Failure

Eligibility:

All Genders

5-19 years

Brief Summary

The goal of this research study is to understand what it is like for a young person to have a sick family member and what it is like to donate bone marrow or stem cells for a sick family member. Prim...

Detailed Description

FOR PARENT or Legal Guardian: Half of the young persons being asked to participate in this study will be donating bone marrow or stem cells and will be referred to as "minor donors." The other half w...

Eligibility Criteria

Inclusion

  • sibling of an allogeneic cell therapy transplant patient -- the persons receiving allogeneic transplant may have either an acquired or congenital disease. Acquired diseases include acute lymphoblastic leukemia, acute myelogenous leukemia, severe aplastic anemia, hemoglobinopathies, and lymphomas.Congenital diseases are comprised of hemoglobinopathies and glycogen/lysosomal disorders. Transplant is being considered after failure to respond to traditional therapies or due to the nature of the disease.
  • 5 to 19 years of age
  • speaks English or Spanish
  • one parent or legal guardian willing to participate
  • mentally able to render a valid assessment
  • donor is harvested at this institution
  • donors will participate in the standard psychosocial intervention
  • children in the non-donor group will be matched by age and gender to donor group participants

Exclusion

  • participation is limited to one donor per family
  • if a child had matched and declined to donate, that child would not be eligible to participate in the non-donor group

Key Trial Info

Start Date :

April 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 1 2011

Estimated Enrollment :

2 Patients enrolled

Trial Details

Trial ID

NCT00667784

Start Date

April 1 2008

End Date

April 1 2011

Last Update

April 2 2012

Active Locations (1)

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1

UT MD Anderson Cancer Center

Houston, Texas, United States, 77030