Status:

SUSPENDED

Bioequivalence Study of Didanosine in Children Treated for HIV

Lead Sponsor:

Assistance Publique - Hôpitaux de Paris

Conditions:

HIV Infections

Eligibility:

All Genders

6-15 years

Phase:

PHASE2

Brief Summary

The purpose of this study is to show that the administration of 400/mg/m2/day of didanosine(ddI) during the meal is bioequivalent to the administration of 240/mg/m2/day of didanosine during fasting, i...

Detailed Description

The didanosine is one of the reverse transcriptase inhibitors. This drug is efficient against the viral replication of the HIV. Licensing for the children was obtained in June, 1992. The main problem ...

Eligibility Criteria

Inclusion

  • Children treated by the didanosine capsules more than 3 months
  • viral load \< 50 copies/ml
  • written informed consent
  • Normal renal function

Exclusion

  • Lack of observance
  • Any treatments which can interact with ddI
  • No written informed consent
  • Weight \> 60 kg

Key Trial Info

Start Date :

September 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2010

Estimated Enrollment :

26 Patients enrolled

Trial Details

Trial ID

NCT00668356

Start Date

September 1 2009

End Date

December 1 2010

Last Update

February 9 2009

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hopital Necker

Paris, France, 75015