Status:
COMPLETED
Combination Pill of Losartan Potassium and Hydrochlorothiazide for Improvement of Medication Compliance Trial
Lead Sponsor:
Kyushu University
Conditions:
Hypertension
Eligibility:
All Genders
20+ years
Phase:
PHASE3
Brief Summary
The purpose of the study is to determine whether combination pill of losartan potassium and hydrochlorothiazide will improve medication compliance among patients with high blood pressure.
Detailed Description
Despite clear evidence that blood pressure lowering treatment is beneficial for reduction of cardiovascular disease, blood pressure levels are not adequately controlled in many hypertensive patients. ...
Eligibility Criteria
Inclusion
- Aged 20 years or above
- Hypertension defined as blood pressure levels of \>/=140/90mmHg or current use of blood pressure lowering drugs
- Able to commence combination therapy of angiotensin receptor antagonists and diuretics
Exclusion
- Blood pressure measurements of \>/=200/120mmHg
- Previous serious adverse events due to angiotensin receptor antagonists or diuretics
- Known or possible pregnancy
- Known severe liver dysfunction
- Known severe kidney disease
- Known contraindication to angiotensin receptor antagonists or diuretics
- Taking \>/=4 tablets except for angiotensin receptor antagonists
- ACE inhibitors, thiazide or thiazide-like diuretics in the morning
- Current participation in another clinical trial
- A high likelihood that the patient is not suitable for the study treatment
Key Trial Info
Start Date :
June 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2011
Estimated Enrollment :
207 Patients enrolled
Trial Details
Trial ID
NCT00670787
Start Date
June 1 2008
End Date
February 1 2011
Last Update
March 7 2011
Active Locations (1)
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1
Department of Medicine and Clinical Science, Kyushu University
Fukuoka, Fukuoka, Japan, 812-8582