Status:
UNKNOWN
Mechanisms of Hypoglycemia Associated Autonomic Failure
Lead Sponsor:
Albert Einstein College of Medicine
Collaborating Sponsors:
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Diabetes Mellitus
Hypoglycemia
Eligibility:
All Genders
21-60 years
Phase:
PHASE2
Brief Summary
Intensive glucose control in type 1 diabetes mellitus (T1DM) is associated with clear health benefits (1). However, despite development of insulin analogs, pump/multi-dose treatment and continuous glu...
Detailed Description
In the prior project period of R01 DK079974, we elucidated the central role played by the opioid signaling system as a mechanism for the development of HAAF/EAAF. We have demonstrated previously that ...
Eligibility Criteria
Inclusion
- Non-diabetic individuals
Exclusion
- Hypertension
- Hyperlipidemia
- Heart disease
- Cerebrovascular disease
- Seizures
- Bleeding disorders
Key Trial Info
Start Date :
March 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2022
Estimated Enrollment :
116 Patients enrolled
Trial Details
Trial ID
NCT00678145
Start Date
March 1 2008
End Date
August 1 2022
Last Update
January 14 2021
Active Locations (1)
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1
Albert Einstein College of Medicine / General Clinical Research Center
The Bronx, New York, United States, 10461